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Citation: Webster et al. Genetic control of human brain transcript expression in Alzheimer disease.
American Journal of Human Genetics, 84(4):445-458 (2009).
Citation: Narayanan et al. Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases.
Molecular systems biology, 10(7): 743 (2014).
Citation: Hokama et al. Altered expression of diabetes-related genes in Alzheimer's disease brains: the Hisayama study.
Cerebral cortex, bht101 (2013).
Citation: Berchtold et al. Gene expression changes in the course of normal brain aging are sexually dimorphic. Proceedings of the National Academy of Sciences, 105(40): 15605-15610 (2008).
Citation: Liang et al. Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain.
Physiol Genomics, 28(3):311-22 (2007).
Liang et al. Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons.
PNAS, 105(11):4441-6 (2008).
Cross-platform normalized (studies included: SE12685, GSE36980, GSE48350, GSE5281, GSE53890, GSE66333,GSE15222)
Differential expression analysis of Cross-platform normalized dataset (stage-1)
Differential expression analysis of Cross-platform normalized dataset (stage-2)
Citation:Webster et al. Genetic control of human brain transcript expression in Alzheimer disease.
American Journal of Human Genetics, 84(4):445-458 (2009).
Citation: Hokama et al. Altered expression of diabetes-related genes in Alzheimer's disease brains: the Hisayama study.
Cerebral cortex, bht101 (2013).
Citation: Liang et al. Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain.
Physiol Genomics, 28(3):311-22 (2007).
Liang et al. Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons.
PNAS, 105(11):4441-6 (2008).
Citation: Tan et al. Genome wide profiling of altered gene expression in the neocortex of Alzheimer's disease.
Journal of neuroscience research, 88(6): 1157-1169 (2010).
Cross-platform normalized (studies included: GSE29652, GSE36980, GSE37263, GSE5281)
Differential expression analysis of Cross-platform normalized dataset (stage-1)
Differential expression analysis of Cross-platform normalized dataset (stage-2)
Citation: Blalock et al. Microarray analyses of laser-captured hippocampus reveal distinct gray and white matter signatures associated with incipient Alzheimer's disease.
Journal of chemical neuroanatomy, 42(2): 118-126 (2011).
Citation: Miller et al. Genes and pathways underlying regional and cell type changes in Alzheimer's disease.
Genome medicine, 5(5): 1 (2013).
Citation: Hokama et al. Altered expression of diabetes-related genes in Alzheimer's disease brains: the Hisayama study.
Cerebral cortex, bht101 (2013).
Citation: Berchtold et al. Gene expression changes in the course of normal brain aging are sexually dimorphic. Proceedings of the National Academy of Sciences, 105(40): 15605-15610 (2008).
Citation: Liang et al. Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain.
Physiol Genomics, 28(3):311-22 (2007).
Liang et al. Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons.
PNAS, 105(11):4441-6 (2008).
Cross-platform normalized (studies included: Dataset of Hippocampus: GSE28146, GSE29378, GSE36980, GSE48350, GSE5281)
Differential expression analysis of Cross-platform normalized dataset
Citation: Durrenberger et al. Selection of novel reference genes for use in the human central nervous system: a BrainNet Europe Study.
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Durrenberger et al. Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet Europe gene expression microarray study.
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Citation: Berchtold et al. Gene expression changes in the course of normal brain aging are sexually dimorphic. Proceedings of the National Academy of Sciences, 105(40): 15605-15610 (2008).
Citation: Liang et al. Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain.
Physiol Genomics, 28(3):311-22 (2007).
Liang et al. Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons.
PNAS, 105(11):4441-6 (2008).
Citation: Berson et al. Cholinergic-associated loss of hnRNP-A/B in Alzheimer's disease impairs cortical splicing and cognitive function in mice.
EMBO molecular medicine, 4(8): 730-742 (2012).
Cross-platform normalized (studies included: GSE26927, GSE26972, GSE48350, GSE5281)
Differential expression analysis of Cross-platform normalized dataset
Detailed information of all samples for differential expression analysis
Gene connectivity in AD network / Control network
RNA-seq data of YAP1 interference/overepression in U251-APP cells
Data and scripts regarding the fine-mapping study of AD risk locus 11p11.2
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