Functional annotation

Functional variants and causal genes for AD GWAS

SNP	CHR	POS	A1	A2	Gene	Location	IGAP_Beta	IGAP_Pvalue	Kunkle_Beta	Kunkle_Pvalue	Jansen_Beta	Jansen_Pvalue	Functional genes
rs439401	19	45414451	T	C	APOE,APOC1	intergenic	-0.361	3.55E-79	-0.382	7.61E-128	-0.061	7.70E-167	TOMM40,APOC1
rs440446	19	45409167	C	G	APOE	exonic	-0.323	2.30E-67	-0.357	2.28E-112	-0.058	1.33E-143	TOMM40,APOC1
rs405509	19	45408836	G	T	APOE	upstream	-0.303	4.35E-73	-0.333	3.11E-114	-0.055	1.37E-145	TOMM40
rs10401176	19	45253491	T	C	BCL3	intronic	-0.214	1.51E-11	-0.160	2.46E-10	-0.037	3.60E-30	-
rs2965169	19	45251156	C	A	BCL3	upstream	-0.237	5.19E-36	-0.206	2.75E-37	-0.035	9.24E-58	ZNF112
rs4803748	19	45247048	T	C	CEACAM16,BCL3	intergenic	-0.237	8.73E-37	-0.201	1.68E-36	-0.035	9.78E-56	PVR,CEACAM19
rs16979372	19	45195313	G	T	CEACAM19,CEACAM16	intergenic	-0.156	8.73E-4	-0.153	6.14E-5	-0.032	4.10E-9	CEACAM19
rs147424543	19	45192912	T	A	CEACAM19,CEACAM16	intergenic	-0.088	0.050	-0.073	0.087	-0.026	1.33E-6	PVR
rs77241309	19	45349177	C	G	PVRL2	upstream	-0.229	3.69E-6	-0.167	1.59E-8	-0.024	4.33E-10	-
rs6064392	20	54984768	T	G	CSTF1,CASS4	intergenic	-0.128	1.11E-5	-0.119	5.17E-6	-0.023	5.19E-9	CASS4,CSTF1
rs17462136	20	54987216	C	G	CASS4	UTR5	-0.134	2.24E-6	-0.123	2.47E-6	-0.023	5.29E-9	CASS4,CSTF1
rs3764643	19	1040382	A	G	ABCA7	intronic	-0.124	0.008	-0.085	0.032	-0.022	5.79E-5	TMEM259,ABCA7
rs7183404	15	59157634	T	C	FAM63B,SLTM	intergenic	-0.056	0.081	-0.036	0.229	-0.022	6.00E-7	FAM63B,FAM81A
rs11603136	11	85874322	C	A	PICALM,EED	intergenic	-0.069	3.57E-5	-0.058	1.11E-4	-0.022	3.67E-5	-
rs1871047	19	45351746	G	A	PVRL2	intronic	-0.141	2.20E-18	-0.145	2.50E-22	-0.022	2.35E-22	PVRL2
rs1871046	19	45351937	C	T	PVRL2	intronic	-0.142	4.33E-18	-0.185	7.74E-31	-0.021	4.00E-22	PVRL2
rs10426423	19	45348253	T	C	BCAM,PVRL2	intergenic	-0.142	3.03E-17	-0.144	1.39E-21	-0.021	8.76E-22	PVRL2
rs1531516	19	45353261	G	C	PVRL2	intronic	-0.146	1.01E-18	-0.152	2.79E-23	-0.021	6.52E-22	PVRL2
rs3752228	19	1041164	T	C	ABCA7	intronic	-0.100	0.035	-0.084	0.035	-0.021	1.27E-4	TMEM259,DAZAP1
rs1532278	8	27466315	T	C	CLU	intronic	-0.143	1.67E-16	-0.126	3.27E-16	-0.020	2.07E-19	CLU
rs4236379	7	5258938	G	T	WIPI2	intronic	-0.039	0.246	-0.026	0.390	-0.020	8.44E-6	RBAK-RBAKDN
rs1532277	8	27466181	T	C	CLU	intronic	-0.139	3.06E-16	-0.126	3.79E-16	-0.020	2.70E-19	CLU
rs1532276	8	27466157	T	C	CLU	intronic	-0.141	5.72E-17	-0.127	1.73E-16	-0.020	2.29E-19	CLU,SCARA3
rs2972569	19	45351891	A	G	PVRL2	intronic	-0.098	9.75E-5	-0.113	2.83E-8	-0.020	1.71E-12	PVR
rs11075777	16	70714287	A	G	MTSS1L	intronic	-0.064	6.67E-5	-0.061	2.66E-5	-0.020	1.93E-4	VAC14
rs4530926	7	5258622	T	C	WIPI2	intronic	-0.026	0.429	-0.021	0.483	-0.020	1.52E-5	WIPI2,RBAK-RBAKDN
rs598726	11	85828548	G	A	PICALM,EED	intergenic	-0.120	2.87E-13	-0.114	6.17E-14	-0.019	8.78E-17	-
rs10426401	19	45147719	G	T	PVR	intronic	-0.113	2.79E-9	-0.111	5.67E-11	-0.019	3.66E-14	PVR
rs76516995	2	127864921	C	G	BIN1	upstream	NA	NA	-0.121	4.83E-10	-0.019	0.238	BIN1
rs2458500	11	85779310	A	G	PICALM	intronic	-0.096	9.03E-7	-0.087	1.21E-6	-0.018	8.37E-12	PICALM
rs2509608	11	85779297	T	G	PICALM	intronic	-0.096	9.06E-7	-0.088	1.19E-6	-0.018	9.15E-12	PICALM
rs3016327	11	85780448	T	C	PICALM	intronic	-0.096	7.46E-7	-0.080	7.26E-6	-0.018	1.12E-11	PICALM
rs2405442	7	99971313	T	C	PILRA	exonic	-0.073	4.23E-5	-0.065	4.37E-5	-0.018	2.66E-15	TRIM4,STAG3,POP7,PILRB,AP4M1,PILRA
rs7926354	11	59962189	A	G	MS4A6A,MS4A4A	intergenic	-0.099	4.22E-10	-0.113	6.96E-15	-0.017	4.93E-14	-
rs10897011	11	59961427	A	G	MS4A6A,MS4A4A	intergenic	-0.099	4.21E-10	-0.113	7.25E-15	-0.017	6.00E-14	-
rs11230180	11	59961486	T	G	MS4A6A,MS4A4A	intergenic	-0.099	5.07E-10	-0.113	8.20E-15	-0.017	6.47E-14	-
rs636317	11	60019150	C	T	MS4A6A,MS4A4A	intergenic	-0.101	1.41E-10	-0.114	5.91E-15	-0.016	2.13E-13	-
rs5158	19	45447178	T	C	APOC4-APOC2	ncRNA_intronic	-0.019	0.464	-0.024	0.286	-0.016	1.12E-6	APOE
rs2509609	11	85779162	C	G	PICALM	intronic	NA	NA	-0.086	1.75E-6	-0.016	2.63E-8	PICALM
rs1140239	16	30021402	T	C	DOC2A	exonic	-0.042	0.008	-0.040	0.006	-0.015	0.004	TAOK2,YPEL3,MAPK3,PPP4C,ASPHD1,TMEM219,INO80E
rs10200967	2	127841769	C	T	BIN1	intronic	-0.087	3.05E-6	-0.097	4.31E-9	-0.015	7.61E-10	BIN1
rs858512	7	99824453	A	G	GATS	intronic	-0.059	9.38E-4	-0.047	0.004	-0.015	4.82E-10	TRIM4,GATS,STAG3,MCM7,ZSCAN21,CNPY4,PILRB,AP4M1,TAF6,PILRA
rs11540084	19	45147340	T	G	PVR	UTR5	-0.096	1.90E-6	-0.099	5.12E-8	-0.015	1.87E-8	PVR
rs1623264	7	99811204	G	C	GATS,STAG3	intronic	-0.061	5.63E-4	-0.046	0.005	-0.015	7.97E-10	TRIM4,GATS,STAG3,ZSCAN21,CNPY4,AP4M1,TAF6,PILRA
rs12148472	15	79231478	C	T	CTSH	intronic	-0.050	0.047	-0.038	0.095	-0.014	6.29E-6	CTSH
rs17854357	11	65601560	C	G	SNX32	exonic	-0.033	0.133	-0.019	0.349	-0.014	3.12E-6	FIBP,CFL1,EFEMP2,RNASEH2C,SNX32
rs2289702	15	79237293	T	C	CTSH	exonic	-0.060	0.053	-0.035	0.213	-0.014	5.18E-5	CTSH
rs13230744	7	99797792	G	A	STAG3	intronic	-0.068	3.82E-4	-0.038	0.022	-0.014	5.52E-9	TRIM4,GATS,STAG3,ZSCAN21,CNPY4,AP4M1,MBLAC1,TAF6,PILRA
rs2231884	11	65656564	T	C	FIBP	upstream	-0.040	0.072	-0.023	0.252	-0.014	2.26E-6	FIBP,CFL1,EFEMP2,RNASEH2C,SNX32
rs55773945	7	100042413	T	C	PPP1R35,C7orf61	intergenic	-0.046	0.004	-0.043	0.004	-0.014	2.25E-10	TRIM4,TSC22D4,MEPCE,PILRB,MBLAC1,PILRA
rs3212930	19	45927610	G	A	ERCC1	upstream	-0.067	6.44E-4	-0.054	0.003	-0.013	7.81E-7	CD3EAP,ERCC1
rs3896609	15	51057868	A	C	SPPL2A	UTR5	-0.084	5.29E-5	-0.068	3.87E-4	-0.013	2.76E-6	SPPL2A,TRPM7,TNFAIP8L3
rs653765	15	59042012	C	T	ADAM10	UTR5	-0.051	0.004	-0.060	1.17E-4	-0.013	3.10E-8	FAM63B
rs78924645	16	31154358	A	G	PRSS36	intronic	-0.062	0.001	-0.043	0.012	-0.013	1.09E-7	RNF40,PRSS36,KAT8
rs75282681	19	45596635	G	A	PPP1R37	exonic	-0.087	1.51E-4	-0.083	2.66E-5	-0.013	3.70E-5	NKPD1
rs1549299	16	31154146	G	A	PRSS36	exonic	-0.055	0.003	-0.042	0.011	-0.013	6.87E-8	STX1B,SETD1A,RNF40,STX4,PRSS36,KAT8,CCDC189
rs17642665	19	45594504	G	C	GEMIN7	UTR3	-0.078	2.73E-4	-0.081	3.26E-5	-0.013	3.42E-5	-
rs77660932	19	45594842	C	T	GEMIN7	downstream	-0.078	2.92E-4	-0.083	2.69E-5	-0.013	4.30E-5	NKPD1
rs4608431	19	45596281	C	A	PPP1R37	upstream	-0.079	2.47E-4	-0.081	3.43E-5	-0.012	4.14E-5	-
rs17562676	19	45601581	A	G	PPP1R37	intronic	-0.075	4.14E-4	-0.082	2.93E-5	-0.012	5.12E-5	-
rs641018	11	65655393	C	G	FIBP	intronic	-0.033	0.100	-0.023	0.216	-0.012	4.46E-6	FIBP,EFEMP2,RNASEH2C,SCYL1,SNX32
rs10417804	19	45595765	A	C	PPP1R37;GEMIN7	upstream;downstream	-0.077	3.15E-4	-0.081	3.41E-5	-0.012	4.46E-5	-
rs10417101	19	45595277	A	G	GEMIN7	downstream	-0.077	3.50E-4	-0.081	3.78E-5	-0.012	4.57E-5	-
rs113708952	19	45595003	C	A	GEMIN7	downstream	-0.076	6.99E-4	-0.082	2.72E-5	-0.012	6.06E-5	NKPD1
rs79587415	19	45607348	T	C	PPP1R37	intronic	-0.076	3.04E-4	-0.080	4.50E-5	-0.012	4.97E-5	-
rs733289	19	45600586	T	G	PPP1R37	intronic	-0.076	4.30E-4	-0.081	3.69E-5	-0.012	5.47E-5	-
rs705867	7	99818927	C	T	PVRIG	UTR3	-0.049	0.002	-0.036	0.011	-0.012	1.75E-8	TRIM56,MEPCE,ZSCAN21,PILRB,AP4M1,LAMTOR4,MBLAC1,ZCWPW1,LAMTOR4,PILRA
rs3852865	19	51714065	A	G	MIR8074,CD33	intergenic	-0.086	3.30E-5	-0.063	2.02E-4	-0.012	1.43E-7	ZNF577
rs35220752	11	85652729	T	C	CCDC83,PICALM	intergenic	-0.098	4.57E-5	-0.101	4.08E-6	-0.012	2.45E-4	-
rs507062	11	65661656	C	T	FOSL1	intronic	-0.034	0.090	-0.022	0.222	-0.012	8.62E-6	FIBP,EFEMP2,RNASEH2C,SCYL1,SNX32
rs10409903	19	45600991	C	T	PPP1R37	intronic	-0.073	8.95E-4	-0.081	3.70E-5	-0.012	7.01E-5	-
rs35991721	7	99728790	T	G	MBLAC1,LAMTOR4	intergenic	-0.071	4.64E-5	-0.058	3.79E-4	-0.012	6.18E-7	TRIM4,GATS,STAG3,ZSCAN21,CNPY4,PILRB,AP4M1,TAF6,PILRA
rs10409727	19	45602862	T	C	PPP1R37	intronic	-0.072	0.001	-0.080	4.03E-5	-0.012	7.58E-5	-
rs2624219	5	86447671	T	A	LOC101929380	ncRNA_intronic	-0.032	0.073	-0.018	0.277	-0.012	1.93E-6	RASA1
rs73154208	7	143092664	G	C	EPHA1	intronic	-0.132	2.83E-6	-0.092	1.01E-4	-0.012	2.51E-4	ZYX
rs2070902	1	161187665	T	C	FCER1G	intronic	-0.049	0.008	-0.046	0.005	-0.012	1.77E-6	NDUFS2,PPOX
rs1534310	7	99699169	T	A	AP4M1,MCM7	UTR5	-0.064	2.51E-4	-0.052	9.91E-4	-0.012	1.37E-6	TRIM4,GATS,STAG3,CNPY4,ZSCAN21,PILRB,AP4M1,PILRA,TAF6
rs2070215	7	99696797	C	T	MCM7	exonic	-0.057	0.001	-0.051	0.001	-0.012	1.92E-6	TRIM4,STAG3,ZSCAN21,CNPY4,AP4M1,TAF6,PILRA
rs4802235	19	45224836	T	G	CEACAM16,BCL3	intergenic	-0.112	6.86E-9	-0.130	1.05E-13	-0.011	2.10E-6	CD3EAP,PVR,CEACAM19,BCL3
rs530324	8	27491186	C	G	SCARA3	upstream	-0.062	1.61E-4	-0.046	0.002	-0.011	2.94E-7	CLU
rs1624099	7	99811313	G	A	GATS,STAG3	intronic	-0.046	0.003	-0.035	0.015	-0.011	1.88E-7	TRIM56,MEPCE,ZSCAN21,PILRB,AP4M1,LAMTOR4,MBLAC1,ZCWPW1,LAMTOR4,PILRA
rs2652817	15	63483290	A	G	RAB8B	intronic	-0.045	0.017	-0.018	0.282	-0.011	1.92E-5	TPM1,RAB8B,LACTB
rs2729791	15	63493057	G	T	RAB8B	intronic	-0.040	0.033	-0.018	0.284	-0.011	2.14E-5	TPM1,RAB8B,LACTB
rs4295	17	61556298	C	G	ACE	intronic	-0.047	0.004	-0.045	0.003	-0.011	8.27E-7	ACE,FTSJ3
rs2526377	17	56410041	G	A	BZRAP1-AS1	ncRNA_intronic	-0.078	1.06E-6	-0.071	1.95E-6	-0.011	7.23E-7	TRIM37,SKA2
rs2632516	17	56409089	C	G	BZRAP1-AS1	ncRNA_intronic	-0.078	9.52E-7	-0.075	3.67E-7	-0.011	7.63E-7	TRIM37,SKA2
rs4292	17	61554341	C	T	ACE	upstream	-0.049	0.003	-0.045	0.003	-0.011	2.19E-6	ACE,FTSJ3,CYB561
rs3814877	16	30042677	T	G	FAM57B	upstream	-0.050	0.002	-0.039	0.009	-0.010	2.32E-6	TAOK2,YPEL3,MAPK3,PPP4C,TMEM219,INO80E,DOC2A
rs4147904	19	1040765	G	A	ABCA7	intronic	-0.100	6.80E-6	-0.091	2.01E-8	-0.010	1.59E-6	-
rs3764642	19	1040046	A	G	ABCA7;CNN2	upstream;downstream	-0.102	3.70E-6	-0.094	7.45E-9	-0.010	1.78E-6	-
rs2526378	17	56404349	G	A	BZRAP1-AS1	ncRNA_intronic	-0.076	1.22E-6	-0.072	7.74E-7	-0.010	2.88E-6	TRIM37
rs1171830	10	61665886	A	C	CCDC6	exonic	-0.034	0.030	-0.036	0.013	-0.010	4.37E-6	CCDC6
rs395601	15	59063196	C	G	FAM63B	upstream	-0.051	0.001	-0.049	9.13E-4	-0.010	5.26E-6	FAM63B,ADAM10
rs8108847	19	1015961	G	A	TMEM259	intronic	-0.044	0.047	-0.046	0.004	-0.010	5.86E-6	-
rs34480360	16	30798689	A	G	ZNF629	upstream	-0.034	0.052	-0.025	0.129	-0.010	3.84E-5	STX1B,RNF40,STX4,PRSS36,ZNF689,KAT8,CCDC189
rs7611795	3	45098350	C	T	CLEC3B,CDCP1	intergenic	-0.100	4.52E-4	-0.120	2.37E-6	-0.010	0.010	ZNF502
rs9874559	3	155337427	C	T	PLCH1	intronic	-0.056	6.01E-4	-0.038	0.012	-0.010	1.22E-5	PLCH1,SLC33A1
rs10212593	3	155347487	T	G	PLCH1	intronic	-0.055	6.31E-4	-0.038	0.012	-0.010	1.42E-5	PLCH1,SLC33A1
rs3747486	16	30786927	T	C	RNF40	UTR3	-0.034	0.053	-0.025	0.128	-0.010	5.47E-5	STX1B,RNF40,STX4,PRSS36,ZNF689,KAT8,CCDC189
rs6463928	7	1595839	A	G	TMEM184A	UTR5	-0.061	6.41E-4	-0.044	0.005	-0.010	1.51E-5	PSMG3,INTS1,NUDT1
rs1171832	10	61667817	G	C	CCDC6,LINC01553	intergenic	-0.033	0.034	-0.036	0.013	-0.010	9.40E-6	CCDC6
rs35713203	16	31090407	C	G	ZNF646	exonic	-0.044	0.006	-0.034	0.023	-0.009	2.29E-5	STX1B,SETD1A,STX4,PRSS36,KAT8,ZNF668,TRIM72,CCDC189
rs7197717	16	31083075	C	A	ZNF668	intronic	-0.040	0.012	-0.036	0.014	-0.009	1.95E-5	STX1B,SETD1A,STX4,PRSS36,KAT8,CCDC189
rs7080009	10	82269461	T	C	TSPAN14	intronic	-0.057	0.004	-0.077	2.18E-5	-0.009	8.58E-4	FAM213A,ANXA11,TSPAN14
rs1870138	10	82269611	A	G	TSPAN14	intronic	-0.058	0.003	-0.076	2.33E-5	-0.009	8.73E-4	FAM213A,ANXA11,TSPAN14
rs58726213	16	31044683	G	A	STX4	intronic	-0.039	0.016	-0.036	0.014	-0.009	4.42E-5	STX1B,SETD1A,RNF40,STX4,PRSS36,KAT8,ZNF668,TRIM72,CCDC189
rs11760769	7	1583941	C	T	TMEM184A	UTR3	-0.056	4.98E-4	-0.042	0.004	-0.009	3.48E-5	PSMG3,INTS1
rs2094473	14	92955508	A	G	SLC24A4	intronic	-0.042	0.022	-0.050	0.002	-0.009	1.72E-4	RIN3
rs12445650	16	31044897	A	G	STX4	UTR5	-0.037	0.021	-0.036	0.016	-0.009	5.18E-5	STX1B,SETD1A,STX4,PRSS36,KAT8,CCDC189
rs514049	15	59042363	A	C	ADAM10	upstream	-0.049	0.002	-0.045	0.002	-0.009	3.49E-5	FAM63B,ADAM10
rs9633740	10	82265271	A	G	TSPAN14	intronic	-0.056	0.005	-0.076	2.69E-5	-0.009	0.001	FAM213A,ANXA11,TSPAN14
rs7896832	10	82257570	T	C	TSPAN14	intronic	-0.057	0.004	-0.075	2.87E-5	-0.009	0.001	FAM213A,ANXA11,TSPAN14
rs1060544	7	99613476	T	C	ZKSCAN1	intronic	NA	NA	-0.054	7.11E-4	-0.009	4.60E-4	TRIM4,GATS,STAG3,CNPY4,ZSCAN21,PILRB,AP4M1,PILRA,TAF6
rs5157	19	45447161	T	C	APOC4-APOC2	ncRNA_intronic	-0.111	5.40E-11	-0.092	6.67E-10	-0.009	5.44E-5	APOE,APOC1
rs12445568	16	31004812	C	T	STX1B	intronic	-0.036	0.028	-0.032	0.030	-0.009	9.11E-5	STX1B,SETD1A,STX4,PRSS36,KAT8,CCDC189
rs344791	19	45829794	C	G	CKM,KLC3	intergenic	-0.047	0.004	-0.044	0.003	-0.008	1.10E-4	CD3EAP,ERCC2
rs344792	19	45829382	A	G	CKM,KLC3	intergenic	-0.046	0.004	-0.046	0.002	-0.008	1.37E-4	CD3EAP,ERCC2
rs73042784	7	1584078	C	T	TMEM184A	UTR3	-0.053	7.58E-4	-0.044	0.003	-0.008	1.78E-4	PSMG3,INTS1
rs1870137	10	82269848	C	G	TSPAN14	intronic	NA	NA	-0.077	2.09E-5	-0.008	0.011	FAM213A,ANXA11,TSPAN14
rs4803823	19	45946399	T	C	MIR6088,FOSB	intergenic	-0.059	0.004	-0.030	0.102	-0.007	0.005	CD3EAP,PPM1N
rs113405869	19	45620513	T	G	PPP1R37	intronic	-0.061	0.008	-0.073	5.91E-4	-0.007	0.051	NKPD1
rs55876153	11	47416636	A	G	SPI1,MIR4487	intergenic	-0.072	1.53E-5	-0.095	4.43E-10	-0.006	0.012	FNBP4,NUP160,C1QTNF4,DDB2,MADD,PSMC3,MTCH2,NDUFS3,SPI1,ACP2
rs2293577	11	47437202	C	T	SLC39A13	UTR3	-0.075	1.05E-5	-0.092	1.22E-9	-0.006	0.011	FNBP4,NUP160,C1QTNF4,MADD,PSMC3,MTCH2,SPI1,ACP2
rs12223593	11	47789082	T	G	FNBP4	upstream	NA	NA	-0.062	4.77E-5	-0.006	0.024	FNBP4,NUP160,MADD,SLC39A13,MTCH2
rs71475909	11	47377283	A	G	SPI1	intronic	NA	NA	-0.084	1.01E-7	-0.005	0.623	FNBP4,NUP160,MADD,MTCH2,SPI1
rs11039200	11	47379646	C	A	SPI1	intronic	-0.075	8.80E-6	-0.092	1.89E-9	-0.005	0.026	FNBP4,C1QTNF4,DDB2,MADD,PSMC3,MTCH2,NDUFS3,SPI1,ACP2
rs10772335	12	10766244	A	C	MAGOHB	upstream	-0.079	3.31E-5	-0.028	0.112	-0.004	0.117	STYK1
rs9921401	16	19919338	G	C	GPRC5B,GPR139	intergenic	-0.068	0.001	-0.086	5.25E-6	-0.004	0.149	KNOP1,KNOP1,GPRC5B
rs2198965	12	10766705	C	G	MAGOHB	upstream	-0.079	2.88E-5	-0.028	0.110	-0.004	0.123	STYK1
rs12102869	16	19918987	C	T	GPRC5B,GPR139	intergenic	-0.067	0.001	-0.087	4.21E-6	-0.004	0.155	KNOP1,GPRC5B
rs6798431	3	128303373	T	C	LINC01565,RPN1	intergenic	-0.075	8.12E-6	-0.043	0.004	-0.003	0.148	RPN1
rs9836257	3	128303483	T	C	LINC01565,RPN1	intergenic	-0.071	1.31E-5	-0.043	0.004	-0.003	0.163	RPN1
rs9289330	3	128311067	G	C	LINC01565,RPN1	intergenic	-0.071	8.69E-6	-0.041	0.005	-0.003	0.248	RPN1
rs35624992	11	47615798	C	G	C1QTNF4	UTR5	NA	NA	-0.086	3.35E-8	-0.002	0.366	FNBP4,NUP160,C1QTNF4,PSMC3,MADD,MTCH2,KBTBD4,NDUFS3,SPI1
rs10734557	11	47380061	A	C	SPI1	intronic	NA	NA	-0.098	1.76E-10	-0.002	0.453	FNBP4,C1QTNF4,DDB2,MADD,PSMC3,MTCH2,NDUFS3,SPI1,ACP2
rs10413237	19	18548249	A	C	ISYNA1	intronic	NA	NA	-0.065	1.53E-5	-0.002	0.509	ISYNA1,ELL,TMEM221
rs72749560	15	82476664	G	A	EFTUD1	intronic	-0.084	6.24E-6	-0.068	1.03E-4	-0.002	0.559	RPS17,CPEB1,SAXO2
rs8006560	14	75349101	C	T	DLST	intronic	0.135	6.80E-6	0.095	2.02E-4	-0.001	0.720	DLST
rs2303696	19	18548884	T	C	ISYNA1	intronic	NA	NA	-0.066	1.89E-5	-0.001	0.830	ELL
rs71642926	1	193599019	C	T	LINC01031,NONE	intergenic	0.084	4.33E-5	0.062	0.001	0.001	0.618	-
rs1542321	11	47379615	A	G	SPI1	intronic	NA	NA	0.098	1.88E-10	0.002	0.447	FNBP4,C1QTNF4,DDB2,MADD,PSMC3,MTCH2,KBTBD4,NDUFS3,SPI1,ACP2
rs28375303	19	18530161	G	T	SSBP4	UTR5	0.075	4.95E-5	0.070	2.02E-5	0.002	0.316	ISYNA1,ELL
rs7257932	19	18527257	A	G	LRRC25,SSBP4	intergenic	0.066	1.53E-4	0.060	1.01E-4	0.003	0.237	ELL
rs2270425	14	75179734	G	C	AREL1	UTR5	0.079	3.02E-5	0.064	2.45E-4	0.003	0.231	AREL1
rs11039376	11	47789549	T	G	FNBP4	upstream	0.060	1.15E-4	0.052	2.81E-4	0.003	0.130	FNBP4,C1QTNF4,NUP160,PSMC3,MADD,MTCH2,NR1H3,SPI1
rs7111606	11	47787538	A	G	FNBP4	intronic	0.060	1.23E-4	0.051	2.95E-4	0.003	0.122	FNBP4,C1QTNF4,NUP160,PSMC3,MADD,MTCH2,NR1H3,SPI1
rs7111576	11	47787445	A	G	FNBP4	intronic	0.060	1.12E-4	0.052	2.92E-4	0.003	0.120	FNBP4,C1QTNF4,NUP160,PSMC3,MADD,MTCH2,NR1H3,SPI1
rs10742814	11	47554337	A	G	CELF1	intronic	0.062	7.39E-5	0.053	1.75E-4	0.003	0.117	FNBP4,C1QTNF4,NUP160,MADD,SLC39A13,MTCH2,SPI1
rs12599324	16	70723404	A	G	VAC14	intronic	0.065	2.88E-5	0.053	1.96E-4	0.004	0.079	VAC14
rs10409483	19	18590223	G	C	ELL	intronic	0.066	5.27E-5	0.062	3.38E-5	0.004	0.088	ISYNA1,ELL
rs11647479	16	70710549	A	C	MTSS1L	intronic	0.067	3.54E-5	0.060	3.16E-5	0.004	0.079	VAC14
rs3826272	16	70725141	A	C	VAC14	intronic	0.062	7.13E-5	0.052	2.89E-4	0.004	0.074	VAC14
rs4985560	16	70724432	A	C	VAC14	intronic	0.064	3.67E-5	0.053	1.87E-4	0.004	0.073	VAC14
rs10425982	19	18586519	A	T	ELL	intronic	0.066	4.49E-5	0.062	3.38E-5	0.004	0.083	ISYNA1,ELL
rs11038913	11	46559730	C	T	AMBRA1	intronic	0.087	0.002	0.118	1.04E-6	0.004	0.251	MADD
rs8103622	19	18572834	T	C	ELL	intronic	0.067	3.29E-5	0.066	1.28E-5	0.004	0.066	ELL
rs6684490	1	40356155	G	A	TRIT1,MYCL	intergenic	0.067	4.81E-4	0.074	1.54E-5	0.004	0.113	TRIT1
rs35874206	16	70720630	G	C	MTSS1L;VAC14	upstream;downstream	0.061	7.97E-5	0.051	4.19E-4	0.004	0.045	VAC14,EXOSC6
rs7258465	19	18533642	C	T	SSBP4	intronic	0.074	2.14E-5	0.066	1.17E-5	0.004	0.054	ELL
rs10427083	19	18550276	A	C	ISYNA1,ELL	intergenic	0.067	5.17E-5	0.063	2.62E-5	0.004	0.050	ELL,TMEM221
rs10442	19	18545341	C	A	ISYNA1,SSBP4	UTR3	0.067	4.46E-5	0.063	2.88E-5	0.004	0.051	ELL
rs6879174	5	139654732	G	A	PFDN1	intronic	0.068	1.74E-5	0.054	1.38E-4	0.004	0.039	PFDN1,SLC4A9,CYSTM1
rs61781270	1	40349428	A	G	TRIT1	upstream	0.067	4.79E-4	0.077	7.11E-6	0.005	0.095	TRIT1
rs4595905	19	18547305	A	T	ISYNA1	intronic	0.067	4.61E-5	0.063	2.85E-5	0.005	0.046	ISYNA1,ELL,TMEM221
rs11075779	16	70723314	C	T	VAC14	intronic	0.065	2.63E-5	0.058	4.86E-5	0.005	0.032	VAC14
rs2385088	19	18545540	G	A	ISYNA1	UTR3	0.069	3.64E-5	0.066	1.26E-5	0.005	0.036	ELL
rs269767	5	139536922	G	A	LOC101929719	ncRNA_exonic	0.066	2.26E-5	0.046	0.001	0.005	0.019	PFDN1,ZMAT2,SLC4A9,CYSTM1
rs34746918	19	18539744	T	C	SSBP4	intronic	0.069	3.05E-5	0.065	1.97E-5	0.005	0.023	ELL
rs3745802	19	46271177	T	G	SIX5	intronic	0.061	8.75E-5	0.062	1.40E-5	0.005	0.015	DMPK
rs635299	19	46274171	C	A	DMPK	intronic	0.064	4.25E-5	0.063	1.03E-5	0.005	0.014	DMPK
rs62111759	19	46296230	T	A	DMWD	upstream	0.063	5.08E-5	0.061	1.85E-5	0.005	0.014	DMPK
rs74486166	11	46700203	C	G	ARHGAP1	UTR3	0.113	1.87E-5	0.113	8.28E-7	0.005	0.128	MADD
rs4913079	5	139683029	G	A	PFDN1	upstream	0.066	1.78E-5	0.053	1.81E-4	0.005	0.013	PFDN1,CYSTM1
rs60356458	19	46234632	C	T	FBXO46	upstream	0.064	5.12E-5	0.061	3.06E-5	0.005	0.013	DMPK,FBXO46
rs1560117	19	18512932	T	C	LRRC25,SSBP4	intergenic	0.063	2.98E-4	0.058	7.79E-5	0.006	0.009	ELL
rs2337138	5	139691664	C	A	PFDN1,HBEGF	intergenic	0.067	1.57E-5	0.055	1.32E-4	0.006	0.008	CYSTM1
rs56024548	17	73084331	T	C	SLC16A5	intronic	0.179	0.004	0.138	0.002	0.007	0.358	NT5C,KCTD2
rs12291515	11	76447123	G	A	GUCY2EP,TSKU	intergenic	0.087	3.87E-4	0.099	8.28E-6	0.007	0.044	-
rs2014576	19	46269076	A	G	SIX5	exonic	0.071	8.68E-6	0.060	3.00E-5	0.007	0.002	DMPK
rs9813845	3	128399623	G	C	RPN1,RAB7A	intergenic	0.066	5.93E-5	0.023	0.127	0.007	0.003	RPN1
rs2712381	3	128338600	A	C	RPN1	downstream	0.066	2.45E-5	0.031	0.031	0.007	0.001	RPN1
rs2811488	3	128336517	C	T	LINC01565,RPN1	intergenic	0.069	1.05E-5	0.031	0.034	0.007	0.001	RPN1
rs2074441	19	1073409	C	G	HMHA1	intronic	0.080	1.60E-5	0.067	5.53E-5	0.008	0.003	POLR2E,ABCA7
rs10086852	8	27238115	G	C	PTK2B	intronic	0.053	6.62E-4	0.051	4.75E-4	0.008	1.54E-4	STMN4,TRIM35,PTK2B
rs2280231	11	47600438	T	C	KBTBD4	UTR5	0.075	1.84E-5	0.067	1.99E-5	0.008	5.99E-4	FNBP4,NUP160,MADD,MTCH2
rs71475921	11	47573342	A	G	CELF1	intronic	0.074	9.85E-6	0.065	2.50E-5	0.009	1.96E-4	FNBP4,NUP160,MADD,MTCH2,SPI1
rs7120548	11	47662932	C	T	MTCH2	intronic	0.072	2.29E-5	0.066	1.48E-5	0.009	1.77E-4	FNBP4,NUP160,MADD,MTCH2,SPI1
rs28371583	1	207494679	G	A	CD55	upstream	0.046	0.008	0.044	0.006	0.009	2.29E-4	CD55
rs117800084	17	73104954	C	T	SLC16A5,ARMC7	intergenic	0.156	0.002	0.124	0.005	0.009	0.191	NT5C,KCTD2
rs117876116	17	73105877	A	G	ARMC7	upstream	0.156	0.002	0.124	0.005	0.009	0.190	NT5C,KCTD2
rs10501320	11	47293799	C	G	MADD	intronic	0.082	2.98E-6	0.089	3.58E-8	0.009	1.46E-4	LRP4,MADD,MTCH2,ARHGAP1,NR1H3
rs79652007	17	73106122	C	A	ARMC7	UTR5	0.198	2.88E-4	0.129	0.003	0.010	0.166	KCTD2
rs9936329	16	31140799	T	G	KAT8	intronic	NA	NA	0.026	0.072	0.010	3.93E-5	SETD1A,KAT8,BCKDK,ZNF668,CCDC189
rs11039159	11	47294021	T	G	MADD	intronic	0.064	5.28E-5	0.069	2.74E-6	0.010	1.38E-5	DDB2,MADD,MTCH2,NR1H3,ACP2
rs56314408	16	31117389	T	C	VKORC1,BCKDK	intergenic	0.041	0.010	0.025	0.083	0.010	7.73E-6	SETD1A,STX4,KAT8,BCKDK,PYDC1,ZNF668,CCDC189
rs11039149	11	47276675	G	A	NR1H3	intronic	0.079	3.65E-6	0.086	3.79E-8	0.010	5.69E-5	DDB2,MADD,MTCH2,NR1H3,ACP2
rs2303222	16	31085470	C	T	ZNF668	UTR5	0.041	0.011	0.027	0.066	0.010	6.03E-6	STX1B,SETD1A,KAT8,BCKDK,ZNF668,CCDC189
rs8050894	16	31104509	G	C	VKORC1	intronic	0.041	0.010	0.028	0.055	0.010	5.66E-6	STX1B,SETD1A,KAT8,BCKDK,ZNF668,CCDC189
rs12716982	16	31128668	A	C	KAT8	upstream	0.043	0.007	0.028	0.061	0.010	5.29E-6	SETD1A,KAT8,BCKDK,ZNF668,CCDC189
rs10401439	19	46320780	T	C	SYMPK	intronic	0.074	9.64E-6	0.070	5.50E-6	0.010	1.48E-5	SYMPK
rs28671692	4	112912462	C	T	PITX2,C4orf32	intergenic	0.022	0.195	0.029	0.068	0.010	1.40E-5	C4orf32,AP1AR,TIFA
rs9939417	16	31053467	T	C	STX4,ZNF668	intergenic	0.038	0.021	0.026	0.079	0.010	4.40E-6	STX1B,SETD1A,STX4,KAT8,BCKDK,ZNF668,CCDC189
rs2032915	16	31117413	T	C	VKORC1,BCKDK	intergenic	0.040	0.015	0.026	0.072	0.010	5.08E-6	SETD1A,KAT8,BCKDK,ZNF668,CCDC189
rs1978487	16	31129942	C	T	KAT8	intronic	0.045	0.006	0.027	0.069	0.010	3.85E-6	SETD1A,KAT8,BCKDK,ZNF668,CCDC189
rs9934438	16	31104878	A	G	VKORC1	intronic	0.037	0.020	0.029	0.050	0.010	3.84E-6	STX1B,SETD1A,STX4,KAT8,BCKDK,ZNF668,CCDC189
rs1171812	10	61655297	C	T	CCDC6	intronic	0.041	0.009	0.035	0.015	0.010	2.60E-6	CCDC6
rs8100672	19	1021637	T	C	TMEM259;RNU6-2	upstream;downstream	NA	NA	0.101	1.28E-7	0.010	9.32E-5	-
rs3850481	4	112912678	A	G	PITX2,C4orf32	intergenic	0.022	0.199	0.029	0.066	0.010	7.84E-6	C4orf32,AP1AR,TIFA
rs7517289	1	161101890	C	A	DEDD	intronic	0.031	0.049	0.034	0.020	0.010	3.03E-6	KLHDC9,NDUFS2,PPOX,B4GALT3,DEDD,NIT1
rs11870474	17	73030810	A	C	NONE,ATP5H	intergenic	0.168	5.43E-4	0.192	2.60E-5	0.010	0.097	NUP85,KCTD2
rs1549293	16	31141993	T	C	KAT8	intronic	0.041	0.013	0.026	0.075	0.010	2.43E-6	SETD1A,KAT8,BCKDK,ZNF668,CCDC189
rs7249244	19	45245698	T	C	CEACAM16,BCL3	intergenic	0.028	0.110	0.047	0.002	0.011	1.18E-6	-
rs10838702	11	47410888	T	G	SPI1,MIR4487	intergenic	0.072	8.98E-6	0.078	6.68E-8	0.011	1.46E-6	FNBP4,NUP160,MADD,SLC39A13,MTCH2,NDUFS3,SPI1
rs7947450	11	47429904	A	G	SLC39A13	upstream	0.072	4.39E-6	0.077	1.22E-7	0.011	1.38E-6	FNBP4,NUP160,MADD,SLC39A13,MTCH2,SPI1
rs11039225	11	47430599	A	G	SLC39A13	intronic	0.072	4.46E-6	0.076	1.32E-7	0.011	1.36E-6	FNBP4,NUP160,MADD,SLC39A13,MTCH2,SPI1
rs55717701	17	73107000	G	A	ARMC7	intronic	0.213	3.37E-4	0.124	0.005	0.011	0.133	NT5C,KCTD2
rs2301287	1	161136843	G	C	PPOX	intronic	0.033	0.041	0.035	0.018	0.011	1.53E-6	KLHDC9,NDUFS2,PPOX,DEDD
rs2301286	1	161136224	A	C	PPOX	UTR5	0.032	0.046	0.036	0.015	0.011	1.43E-6	KLHDC9,NDUFS2,PPOX,DEDD
rs7199618	16	70673517	A	G	IL34	intronic	NA	NA	NA	NA	0.011	1.07E-5	IL34,EXOSC6
rs7103808	11	60078176	G	A	MS4A4A,MS4A6E	intergenic	0.070	2.24E-5	0.076	6.51E-7	0.011	2.53E-6	-
rs7191249	16	70669268	T	C	IL34	intronic	0.033	0.045	0.019	0.195	0.011	2.28E-6	IL34,WWP2,EXOSC6
rs1968489	4	113034504	C	T	PITX2,C4orf32	intergenic	0.012	0.507	0.021	0.190	0.011	5.12E-6	TIFA
rs7210163	17	73031190	A	G	NONE,ATP5H	intergenic	0.187	1.54E-4	0.202	1.09E-5	0.011	0.094	ATP5H,KCTD2
rs117863671	17	73098838	A	T	SLC16A5	intronic	0.159	0.002	0.123	0.005	0.011	0.120	NT5C,ATP5H,KCTD2
rs4467218	2	127783276	C	G	GYPC,BIN1	intergenic	0.037	0.061	0.051	0.004	0.011	1.92E-5	-
rs2965155	19	45188471	T	C	CEACAM19	downstream	0.047	0.003	0.030	0.037	0.011	1.39E-7	CEACAM19
rs35917075	17	73017481	G	A	ICT1	downstream	0.191	1.15E-4	0.192	4.53E-5	0.011	0.123	NT5C,ATP5H,KCTD2
rs6509201	19	45714978	A	C	EXOC3L2	downstream	NA	NA	0.117	6.32E-9	0.011	2.63E-6	-
rs12943281	17	73030094	A	G	NONE,ATP5H	intergenic	0.189	1.32E-4	0.202	1.07E-5	0.012	0.054	ATP5H,KCTD2
rs3813905	16	70680850	G	C	IL34	UTR5	0.036	0.033	0.018	0.226	0.012	3.49E-7	WWP2,EXOSC6
rs10797093	1	161103445	G	T	DEDD	upstream	0.032	0.057	0.036	0.019	0.012	6.25E-7	KLHDC9,NDUFS2,PPOX
rs11583045	1	161100336	A	T	DEDD	intronic	NA	NA	0.037	0.022	0.012	4.38E-6	KLHDC9,NDUFS2,PPOX
rs7218004	17	73028843	A	G	ICT1,ATP5H	intergenic	0.187	1.60E-4	0.209	8.54E-6	0.012	0.088	ATP5H,KCTD2
rs3754609	2	127829943	C	T	BIN1	intronic	0.048	0.018	0.062	7.15E-4	0.012	6.93E-6	-
rs12459074	19	45608832	C	G	PPP1R37	intronic	0.058	0.001	0.053	0.001	0.012	6.16E-7	-
rs76016560	17	4891092	A	G	CAMTA2;INCA1	upstream;downstream	0.076	0.001	0.047	0.032	0.012	1.94E-4	ZNF232
rs10908826	1	161172525	T	C	NDUFS2	intronic	0.019	0.400	0.010	0.611	0.013	3.90E-5	NDUFS2
rs6464547	7	143083661	A	C	ZYX	intronic	0.094	2.31E-6	0.060	2.36E-4	0.013	9.47E-9	-
rs3760629	19	45458146	C	A	CLPTM1	intronic	0.098	3.77E-10	0.106	1.22E-13	0.013	9.89E-10	APOE,APOC1
rs10426750	19	45457684	C	G	CLPTM1	upstream	0.099	2.77E-10	0.105	1.76E-13	0.013	7.51E-10	APOE,APOC1
rs7248162	19	45454686	C	T	APOC4-APOC2,CLPTM1	intergenic	0.104	5.51E-11	0.106	1.14E-13	0.013	5.42E-10	APOE,APOC1
rs3813623	1	161169165	T	G	NDUFS2	UTR5	0.023	0.288	0.009	0.660	0.013	1.85E-5	NDUFS2
rs1131885	7	143088526	C	T	EPHA1	UTR3	0.092	2.24E-6	0.061	1.57E-4	0.014	2.54E-9	-
rs3809846	17	4902564	C	T	KIF1C	intronic	0.073	0.003	0.044	0.058	0.014	6.80E-5	RABEP1,PLD2,ZNF232,MINK1,SPAG7
rs11234552	11	85846187	G	A	PICALM,EED	intergenic	0.066	5.90E-4	0.047	0.007	0.014	2.75E-7	PICALM
rs7252480	19	45458925	T	C	CLPTM1	intronic	0.077	1.19E-5	0.079	6.39E-7	0.014	4.15E-9	APOC1
rs2238682	19	45458593	T	C	CLPTM1	UTR5	0.084	3.26E-6	0.080	4.87E-7	0.014	2.50E-9	APOC1
rs75364577	19	1028149	A	G	CNN2	intronic	0.183	1.19E-6	0.109	3.93E-6	0.014	2.00E-6	-
rs1004173	6	47445017	T	C	CD2AP	upstream	0.097	4.55E-8	0.083	1.76E-7	0.014	5.64E-9	-
rs4147929	19	1063443	A	G	ABCA7	intronic	0.135	1.70E-9	0.122	9.56E-10	0.014	4.43E-7	POLR2E,ABCA7
rs11234562	11	85863769	G	T	PICALM,EED	intergenic	0.069	3.70E-4	0.048	0.007	0.014	1.27E-7	PICALM
rs76101349	17	4902473	T	C	KIF1C	intronic	0.085	0.001	0.069	0.007	0.015	1.06E-4	SPNS2,ZNF232
rs7158555	14	53362006	G	A	FERMT2	intronic	0.092	2.86E-4	0.086	2.09E-4	0.015	1.80E-5	ERO1A
rs4732729	8	27461492	A	C	CLU	intronic	0.109	1.26E-9	0.099	8.00E-10	0.015	9.63E-11	SCARA3
rs3807475	7	100026292	A	G	ZCWPW1	UTR5	0.072	8.24E-4	0.073	2.29E-4	0.015	3.86E-7	MEPCE,ZSCAN21,PILRB,AP4M1,PILRA
rs2283568	17	4852305	A	G	PFN1	UTR5	0.072	0.011	0.051	0.023	0.015	1.28E-5	PLD2,ZNF232,MINK1,SPAG7
rs755951	8	27226790	C	A	PTK2B	intronic	0.082	1.99E-7	0.082	3.79E-8	0.015	1.13E-11	PTK2B
rs4727455	7	100070680	A	G	TSC22D4	intronic	0.071	0.001	0.077	1.23E-4	0.015	2.53E-7	MEPCE,ZSCAN21,PILRB,AP4M1,PILRA
rs73223431	8	27219987	T	C	PTK2B	intronic	0.091	1.38E-8	0.094	8.34E-10	0.015	1.09E-11	TRIM35,PTK2B
rs2965156	19	45188429	G	C	CEACAM19	downstream	0.053	0.001	0.056	1.42E-4	0.015	1.18E-12	PVR,CEACAM19
rs35577563	19	45504349	G	C	RELB	upstream	0.102	2.68E-9	0.090	4.76E-9	0.015	2.85E-12	APOC1,CLPTM1
rs16954243	17	4812403	T	A	CHRNE,GP1BA	intergenic	0.121	8.30E-5	0.085	5.65E-4	0.015	2.86E-5	ZNF232,SPAG7
rs13236234	7	99963018	C	T	STAG3L5P-PVRIG2P-PILRB	ncRNA_intronic	0.068	0.001	0.065	0.001	0.016	1.28E-7	MEPCE,ZSCAN21,PILRB,PILRA
rs72835022	17	4757729	C	G	MINK1	intronic	0.115	1.81E-5	0.091	2.41E-4	0.016	2.79E-5	PLD2,ZNF232,SPAG7
rs2302315	17	4806428	A	G	CHRNE;C17orf107	upstream;downstream	0.112	3.49E-5	0.088	3.57E-4	0.016	1.75E-5	ZNF232,SPAG7
rs79436576	17	4805167	T	C	C17orf107	UTR3	0.116	4.79E-5	0.089	3.06E-4	0.016	2.10E-5	ZNF232
rs11585858	1	161156033	A	C	B4GALT3,ADAMTS4	intergenic	0.049	0.010	0.037	0.027	0.016	5.05E-10	NDUFS2
rs113426708	17	4823657	A	G	CHRNE,GP1BA	intergenic	0.109	5.26E-5	0.085	5.95E-4	0.016	1.53E-5	SPNS2,ZNF232,SPAG7
rs56067981	17	4801966	A	G	CHRNE	UTR3	0.118	1.43E-5	0.090	2.58E-4	0.016	1.43E-5	ZNF232,NUP88,SPAG7
rs61975652	14	92859161	A	G	SLC24A4	intronic	0.056	0.021	0.051	0.019	0.016	4.29E-6	-
rs79999495	5	176936194	C	G	DOK3	intronic	0.117	0.003	0.118	7.91E-4	0.016	3.55E-4	FAM193B
rs2161110	5	176936272	T	G	DOK3	intronic	0.117	0.003	0.118	9.66E-4	0.016	3.87E-4	FAM193B
rs4575098	1	161155392	A	G	B4GALT3,ADAMTS4	intergenic	0.041	0.025	0.038	0.023	0.016	1.90E-10	NDUFS2
rs34461890	17	4806718	C	T	CHRNE;C17orf107	upstream;downstream	0.121	1.07E-5	0.085	5.09E-4	0.016	8.09E-6	ZNF232,SPAG7
rs13032148	2	127865100	A	G	BIN1	upstream	0.106	1.87E-10	0.103	1.01E-11	0.017	8.73E-13	BIN1
rs2242320	5	176943673	T	C	DDX41	intronic	0.158	6.06E-4	0.114	9.20E-4	0.017	1.88E-4	FAM193B
rs335455	5	176972620	C	T	FAM193B	intronic	0.133	2.43E-4	0.103	0.002	0.018	1.54E-5	FAM193B
rs3749728	5	176936819	G	C	DOK3	exonic	0.117	0.003	0.113	0.001	0.018	4.16E-5	FAM193B
rs56229705	17	5014789	A	G	ZNF232	intronic	0.088	5.87E-4	0.054	0.021	0.018	1.00E-7	RABEP1,ZNF232,NUP88,SPAG7
rs117618017	15	63569902	T	C	APH1B	exonic	0.077	0.063	0.094	2.38E-4	0.018	3.44E-8	APH1B
rs2112181	5	176936590	C	T	DOK3	exonic	0.118	0.002	0.113	0.001	0.018	3.69E-5	FAM193B
rs56152541	17	5001027	C	T	ZFP3,ZNF232	intergenic	0.083	0.002	0.046	0.050	0.018	4.69E-8	RABEP1,ZNF232,NUP88,SPAG7
rs10406449	19	1040773	A	G	ABCA7	intronic	NA	NA	0.082	0.038	0.018	0.001	TMEM259
rs113151753	17	5185365	G	C	RABEP1	upstream	0.103	2.24E-5	0.075	5.51E-4	0.018	1.80E-8	RABEP1,SPNS2,ZNF232,NUP88
rs7124396	11	47787434	T	G	FNBP4	intronic	0.057	2.33E-4	0.050	4.44E-4	0.018	6.05E-4	FNBP4,C1QTNF4,NUP160,MADD,MTCH2,NDUFS3,SPI1
rs78710909	2	127864922	C	G	BIN1	upstream	NA	NA	0.105	4.44E-7	0.018	0.245	BIN1
rs73336014	5	176966623	C	T	FAM193B	intronic	0.131	2.72E-4	0.108	0.001	0.018	1.51E-5	FAM193B
rs12618593	2	127886371	C	T	BIN1,CYP27C1	intergenic	0.126	7.77E-13	0.125	2.87E-15	0.020	6.16E-17	BIN1
rs13025717	2	127886158	T	C	BIN1,CYP27C1	intergenic	0.126	7.94E-13	0.125	2.98E-15	0.020	5.98E-17	BIN1
rs13025765	2	127886233	T	C	BIN1,CYP27C1	intergenic	0.126	7.87E-13	0.125	3.25E-15	0.020	5.94E-17	BIN1
rs12617835	2	127886416	C	A	BIN1,CYP27C1	intergenic	0.126	7.70E-13	0.125	2.84E-15	0.020	5.50E-17	BIN1
rs75511804	17	5138304	T	C	LOC100130950	ncRNA_exonic	0.106	9.61E-6	0.085	1.14E-4	0.020	1.46E-9	RABEP1,SPNS2,ZNF232,NUP88
rs11554586	2	127864546	A	G	BIN1	UTR5	0.101	1.53E-6	0.093	4.18E-7	0.021	1.03E-13	-
rs113683483	7	99679295	T	C	ZNF3	UTR5	0.083	0.032	0.045	0.151	0.023	2.36E-6	ZSCAN21
rs7251911	19	45582402	G	C	GEMIN7	upstream	0.095	0.198	0.122	2.93E-4	0.025	1.85E-10	EML2
rs35194062	19	45505177	A	C	RELB	intronic	0.221	5.67E-7	0.305	2.38E-14	0.027	1.37E-7	-
rs4452060	19	45347911	A	C	BCAM,PVRL2	intergenic	0.200	1.29E-31	0.183	2.82E-33	0.032	1.24E-49	TOMM40
rs2927487	19	45225973	G	C	CEACAM16,BCL3	intergenic	0.224	4.23E-23	0.198	5.23E-23	0.033	3.91E-31	TOMM40,CEACAM19
rs10424517	19	45596517	A	G	PPP1R37	UTR5	NA	NA	0.106	9.85E-7	0.034	0.023	-
rs10410833	19	45668327	T	C	TRAPPC6A	intronic	0.269	2.81E-19	0.215	1.39E-15	0.046	1.37E-32	TRAPPC6A
rs12162222	19	45348522	T	G	PVRL2	upstream	0.330	3.89E-72	0.290	5.22E-73	0.054	4.11E-110	CEACAM19
rs117316645	19	45458212	A	G	CLPTM1	intronic	0.239	4.26E-11	0.271	8.95E-15	0.055	4.78E-24	-
rs12459810	19	45249661	T	C	CEACAM16,BCL3	intergenic	0.327	6.77E-43	0.218	7.50E-34	0.083	4.08E-44	CEACAM19
rs117612135	19	45504527	T	C	RELB	upstream	0.797	2.08E-18	0.517	6.59E-12	0.141	6.26E-47	-

^aNote:

CHR: chromasome; POS: position; A1: alternative allele; A2: reference allele; IGAP_beta: GWAS beta value from the Lambert study; IGAP_Pvalue: GWAS P value from the Lambert study (Lambert et al., 2013); Kunkle_beta: GWAS beta value from the Kunkle study; Kunkle_Pvalue: GWAS P value from the Kunkle study (Kunkle et al., 2019); Jansen_beta: GWAS beta value from the Jansen study; Jansen_Pvalue: GWAS P value from the Jansen study (Jansen et al., 2019); Histone_mod: total number of datasets that had histone modification peaks (false discovery rate, FDR<0.001) overlapping with the target variant; ATAC: total number of assay for transposase-accessible chromatin with high throughput sequencing (ATAC-seq) datasets that had open chromatin peaks overlapping with the target variant (FDR<0.001); diffTF: total number of transcriptional factors (TFs) that could bind to the DNA element harboring the target variant (FDR<0.05) and binding affinities of these TFs with the DNA element were predicted to be significantly affected by different alleles of the target variant (P_rank<0.05); eQTL: expressional quantitive loci (eQTL) gene for the target variant (P<0.001).